Publications
Here you will find our disseminated work.
Research Highlights
A genome-wide association analysis reveals new pathogenic pathways in gout.
Nature genetics
·
15 Oct 2024
·
pubmed:39406924
All
2025
Reduced Weight Gain with Pioglitazone vs Vildagliptin in
Diabetes, metabolic syndrome and obesity : targets and therapy
·
23 Apr 2025
·
pubmed:40297769
Colocalization Analysis Reveals Shared Genetic Loci Contributing to Gout and Metabolite Levels
Gout, Urate, and Crystal Deposition Disease
·
27 Mar 2025
·
doi:10.3390/gucdd3020006
Hyperuricaemia and gout in the Pacific.
Nature reviews. Rheumatology
·
11 Mar 2025
·
pubmed:40069386
A rare splice-site variant in TNNT2: the need for ancestral diversity in genomic reference data sets.
European heart journal
·
05 Mar 2025
·
pubmed:40038847
2024
Gout-associated SNP at the IL1RN-IL1F10 region is associated with altered cytokine production in PBMCs of patients with gout and controls.
Arthritis research & therapy
·
20 Nov 2024
·
pubmed:39568029
Culturally responsive strategies and practical considerations for live tissue studies in Māori participant cohorts.
Frontiers in research metrics and analytics
·
05 Nov 2024
·
pubmed:39564513
Publisher Correction: A genome-wide association analysis reveals new pathogenic pathways in gout.
Nature genetics
·
01 Nov 2024
·
pubmed:39501129
The population-specific Thr44Met OCT3 coding variant affects metformin pharmacokinetics with subsequent effects on insulin sensitivity in C57Bl/6J mice
Diabetologia
·
18 Oct 2024
·
doi:10.1007/s00125-024-06287-1
The population-specific Thr44Met OCT3 coding variant affects metformin pharmacokinetics with subsequent effects on insulin sensitivity in C57Bl/6J mice.
Diabetologia
·
18 Oct 2024
·
pubmed:39422716
A genome-wide association analysis reveals new pathogenic pathways in gout
Nature Genetics
·
15 Oct 2024
·
doi:10.1038/s41588-024-01921-5
A genome-wide association analysis reveals new pathogenic pathways in gout.
Nature genetics
·
15 Oct 2024
·
pubmed:39406924
A Polynesian-specific SLC22A3 variant associates with low plasma lipoprotein(a) concentrations independent of apo(a) isoform size in males.
Bioscience reports
·
31 Jul 2024
·
pubmed:38896441
The pathogenesis of gout: molecular insights from genetic, epigenomic and transcriptomic studies.
Nature reviews. Rheumatology
·
11 Jul 2024
·
pubmed:38992217
Further delineation of short-chain enoyl-CoA hydratase deficiency in the Pacific population.
Molecular genetics and metabolism
·
25 May 2024
·
pubmed:38820906
The gout epidemic in French Polynesia: a modelling study of data from the Ma'i u'u epidemiological survey.
The Lancet. Global health
·
01 Apr 2024
·
pubmed:38485432
Interaction of genetic variation at ADH1B and MLXIPL with alcohol consumption for elevated serum urate level and gout among people of European ethnicity.
Arthritis research & therapy
·
08 Feb 2024
·
pubmed:38331848
2023
Genetic testing for misclassified monogenic diabetes in Māori and Pacific peoples in Aōtearoa New Zealand with early-onset type 2 diabetes.
Frontiers in endocrinology
·
10 May 2023
·
pubmed:37234800
A Polynesian
HGG advances
·
08 May 2023
·
pubmed:37250494
A functional genomics approach reveals suggestive quantitative trait loci associated with combined TLR4 and BCP crystal-induced inflammation and osteoarthritis.
Osteoarthritis and cartilage
·
25 Apr 2023
·
pubmed:37105395
Association of Gout Polygenic Risk Score With Age at Disease Onset and Tophaceous Disease in European and Polynesian Men With Gout.
Arthritis & rheumatology (Hoboken, N.J.)
·
25 Mar 2023
·
pubmed:36281732
Genetic and Physiological Effects of Insulin-Like Growth Factor-1 (IGF-1) on Human Urate Homeostasis.
Journal of the American Society of Nephrology : JASN
·
13 Jan 2023
·
pubmed:36735516
Stratified glucose-lowering response to vildagliptin and pioglitazone by obesity and hypertriglyceridemia in a randomized crossover trial.
Frontiers in endocrinology
·
09 Jan 2023
·
pubmed:36699039
2022
A Polynesian-specific copy number variant encompassing the MICA gene associates with gout.
Human molecular genetics
·
28 Oct 2022
·
pubmed:35451026
Local genetic covariance between serum urate and kidney function estimated with Bayesian multitrait models.
G3 (Bethesda, Md.)
·
25 Aug 2022
·
pubmed:35876900
Local genetic covariance between serum urate and kidney function estimated with Bayesian multitrait models
G3 Genes|Genomes|Genetics
·
25 Jul 2022
·
doi:10.1093/g3journal/jkac158
SNVformer: An Attention-based Deep Neural Network for GWAS Data
Cold Spring Harbor Laboratory
·
10 Jul 2022
·
doi:10.1101/2022.07.07.499217
Genetic association studies of the progression from hyperuricaemia to gout.
Rheumatology (Oxford, England)
·
30 May 2022
·
pubmed:35020833
2021
Riboceine Rescues Auranofin-Induced Craniofacial Defects in Zebrafish.
Antioxidants (Basel, Switzerland)
·
08 Dec 2021
·
pubmed:34943067
The genetic basis of urate control and gout: Insights into molecular pathogenesis from follow-up study of genome-wide association study loci.
Best practice & research. Clinical rheumatology
·
01 Nov 2021
·
pubmed:34732286
Evolution and genomic organization of the insect sHSP gene cluster and coordinate regulation in phenotypic plasticity
BMC Ecology and Evolution
·
04 Aug 2021
·
doi:10.1186/s12862-021-01885-8
Evolution and genomic organization of the insect sHSP gene cluster and coordinate regulation in phenotypic plasticity.
BMC ecology and evolution
·
04 Aug 2021
·
pubmed:34348652
Genetic and Physiological Effects of Insulin on Human Urate Homeostasis.
Frontiers in physiology
·
02 Aug 2021
·
pubmed:34408667
Gout, Rheumatoid Arthritis, and the Risk of Death Related to Coronavirus Disease 2019: An Analysis of the UK Biobank.
ACR open rheumatology
·
15 Apr 2021
·
pubmed:33856739
Local genetic covariance between serum urate and kidney function obtained from local Bayesian regressions
Cold Spring Harbor Laboratory
·
05 Apr 2021
·
doi:10.1101/2021.03.31.21254729
Evolution and genomic organization of the sHSP gene cluster in Arthropods
Springer Science and Business Media LLC
·
05 Feb 2021
·
doi:10.21203/rs.3.rs-192223/v1
2020
Gout, rheumatoid arthritis and the risk of death from COVID-19: an analysis of the UK Biobank
Cold Spring Harbor Laboratory
·
09 Nov 2020
·
doi:10.1101/2020.11.06.20227405
The Shared Genetic Basis of Hyperuricemia, Gout, and Kidney Function
Seminars in Nephrology
·
01 Nov 2020
·
doi:10.1016/j.semnephrol.2020.12.002
The Shared Genetic Basis of Hyperuricemia, Gout, and Kidney Function.
Seminars in nephrology
·
01 Nov 2020
·
pubmed:33678313
Genome Architecture Facilitates Phenotypic Plasticity in the Honeybee (Apis mellifera).
Molecular biology and evolution
·
01 Jul 2020
·
pubmed:32134461
Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control.
Human molecular genetics
·
15 Apr 2020
·
pubmed:31985003
Genome Architecture Facilitates Phenotypic Plasticity in the Honeybee (Apis mellifera)
Molecular Biology and Evolution
·
05 Apr 2020
·
doi:10.1093/molbev/msaa057
Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control
Human Molecular Genetics
·
27 Jan 2020
·
doi:10.1093/hmg/ddaa013
2019
Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control
Cold Spring Harbor Laboratory
·
22 Aug 2019
·
doi:10.1101/743864
Corrigendum: Functional Urate-Associated Genetic Variants Influence Expression of lincRNAs LINC01229 and MAFTRR
Frontiers in Genetics
·
24 Apr 2019
·
doi:10.3389/fgene.2019.00382
Corrigendum: Functional Urate-Associated Genetic Variants Influence Expression of lincRNAs
Frontiers in genetics
·
24 Apr 2019
·
pubmed:31105747
Molecular evolutionary trends and feeding ecology diversification in the Hemiptera, anchored by the milkweed bug genome
Genome Biology
·
02 Apr 2019
·
doi:10.1186/s13059-019-1660-0
Molecular evolutionary trends and feeding ecology diversification in the Hemiptera, anchored by the milkweed bug genome.
Genome biology
·
02 Apr 2019
·
pubmed:30935422
Functional Urate-Associated Genetic Variants Influence Expression of lincRNAs
Frontiers in genetics
·
21 Jan 2019
·
pmid:30719032
Functional Urate-Associated Genetic Variants Influence Expression of lincRNAs
Frontiers in genetics
·
21 Jan 2019
·
pubmed:30719032
2018
A non-coding genetic variant maximally associated with serum urate levels is functionally linked to HNF4A-dependent PDZK1 expression.
Human molecular genetics
·
15 Nov 2018
·
pmid:30124855
A non-coding genetic variant maximally associated with serum urate levels is functionally linked to HNF4A-dependent PDZK1 expression.
Human molecular genetics
·
15 Nov 2018
·
pubmed:30124855
Antioxidant treatment ameliorates phenotypic features of SMC1A-mutated Cornelia de Lange syndrome in vitro and in vivo.
Human molecular genetics
·
01 Sep 2018
·
pmid:29860495
Antioxidant treatment ameliorates phenotypic features of SMC1A-mutated Cornelia de Lange syndrome in vitro and in vivo.
Human molecular genetics
·
01 Sep 2018
·
pubmed:29860495
A non-coding genetic variant maximally associated with serum urate levels is functionally linked to HNF4A-dependent PDZK1 expression
Cold Spring Harbor Laboratory
·
08 Jul 2018
·
doi:10.1101/362277
2017
The meiotic regulator JASON utilizes alternative translation initiation sites to produce differentially localized forms.
Journal of experimental botany
·
10 Jul 2017
·
pmid:28922756
The meiotic regulator JASON utilizes alternative translation initiation sites to produce differentially localized forms.
Journal of experimental botany
·
10 Jul 2017
·
pubmed:28922756
An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations
Scientific Reports
·
09 May 2017
·
doi:10.1038/s41598-017-01519-4
2015
The genomes of two key bumblebee species with primitive eusocial organization
Genome Biology
·
24 Apr 2015
·
doi:10.1186/s13059-015-0623-3
The genomes of two key bumblebee species with primitive eusocial organization.
Genome biology
·
24 Apr 2015
·
pubmed:25908251
What Do Studies of Insect Polyphenisms Tell Us about Nutritionally-Triggered Epigenomic Changes and Their Consequences?
Nutrients
·
11 Mar 2015
·
doi:10.3390/nu7031787
What do studies of insect polyphenisms tell us about nutritionally-triggered epigenomic changes and their consequences?
Nutrients
·
11 Mar 2015
·
pubmed:25768950
2014
The importance of early life in childhood obesity and related diseases: a report from the 2014 Gravida Strategic Summit
Journal of Developmental Origins of Health and Disease
·
13 Oct 2014
·
doi:10.1017/S2040174414000488
2013
The pea aphid (Acyrthosiphon pisum) genome encodes two divergent early developmental programs
Developmental Biology
·
01 May 2013
·
doi:10.1016/j.ydbio.2013.01.036
The pea aphid (Acyrthosiphon pisum) genome encodes two divergent early developmental programs.
Developmental biology
·
13 Feb 2013
·
pubmed:23416037